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Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1

Temperature affects functions of all ion channels, but few of them can be gated directly. The vanilloid receptor VR1 provides one exception. As a pain receptor, it is activated by heat >42°C in addition to other noxious stimuli, e.g. acids and vanilloids. Although it is understood how ligand- and...

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Detalhes bibliográficos
Main Authors: Liu, Beiying, Hui, Kwokyin, Qin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303577/
https://ncbi.nlm.nih.gov/pubmed/14581201
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