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Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1

Temperature affects functions of all ion channels, but few of them can be gated directly. The vanilloid receptor VR1 provides one exception. As a pain receptor, it is activated by heat >42°C in addition to other noxious stimuli, e.g. acids and vanilloids. Although it is understood how ligand- and...

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Autores principales: Liu, Beiying, Hui, Kwokyin, Qin, Feng
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2003
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303577/
https://ncbi.nlm.nih.gov/pubmed/14581201
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