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Thermodynamics of Heat Activation of Single Capsaicin Ion Channels VR1

Temperature affects functions of all ion channels, but few of them can be gated directly. The vanilloid receptor VR1 provides one exception. As a pain receptor, it is activated by heat >42°C in addition to other noxious stimuli, e.g. acids and vanilloids. Although it is understood how ligand- and...

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Autors principals: Liu, Beiying, Hui, Kwokyin, Qin, Feng
Format: Artigo
Idioma:Inglês
Publicat: Biophysical Society 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303577/
https://ncbi.nlm.nih.gov/pubmed/14581201
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