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Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

Thermal TRP channels are important for thermal sensation and nociception, but their gating mechanisms have remained elusive. With optically generated submillisecond temperature steps from 22°C to >60°C, we have directly measured the activation and deactivation kinetics of TRPV1 channels, and from...

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Autors principals: Yao, Jing, Liu, Beiying, Qin, Feng
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941006/
https://ncbi.nlm.nih.gov/pubmed/20858418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.022
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