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Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

Thermal TRP channels are important for thermal sensation and nociception, but their gating mechanisms have remained elusive. With optically generated submillisecond temperature steps from 22°C to >60°C, we have directly measured the activation and deactivation kinetics of TRPV1 channels, and from...

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Detalles Bibliográficos
Main Authors: Yao, Jing, Liu, Beiying, Qin, Feng
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941006/
https://ncbi.nlm.nih.gov/pubmed/20858418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.022
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