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Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

Thermal TRP channels are important for thermal sensation and nociception, but their gating mechanisms have remained elusive. With optically generated submillisecond temperature steps from 22°C to >60°C, we have directly measured the activation and deactivation kinetics of TRPV1 channels, and from...

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Detalhes bibliográficos
Main Authors: Yao, Jing, Liu, Beiying, Qin, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941006/
https://ncbi.nlm.nih.gov/pubmed/20858418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.022
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