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Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

Thermal TRP channels are important for thermal sensation and nociception, but their gating mechanisms have remained elusive. With optically generated submillisecond temperature steps from 22°C to >60°C, we have directly measured the activation and deactivation kinetics of TRPV1 channels, and from...

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Autori principali: Yao, Jing, Liu, Beiying, Qin, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941006/
https://ncbi.nlm.nih.gov/pubmed/20858418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.022
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