The Integrity of the TRP Domain Is Pivotal for Correct TRPV1 Channel Gating

Transient receptor potential vanilloid subtype I (TRPV1) is a thermosensory ion channel that is also gated by chemical substances such as vanilloids. Adjacent to the channel gate, this polymodal thermoTRP channel displays a TRP domain, referred to as AD1, that plays a role in subunit association and...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Gregorio-Teruel, Lucia, Valente, Pierluigi, Liu, Beiying, Fernández-Ballester, Gregorio, Qin, Feng, Ferrer-Montiel, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2015
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572506/
https://ncbi.nlm.nih.gov/pubmed/26244735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.039
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