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Mutation of I696 and W697 in the TRP box of vanilloid receptor subtype I modulates allosteric channel activation
The transient receptor potential vanilloid receptor subtype I (TRPV1) channel acts as a polymodal sensory receptor gated by chemical and physical stimuli. Like other TRP channels, TRPV1 contains in its C terminus a short, conserved domain called the TRP box, which is necessary for channel gating. Su...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3933934/ https://ncbi.nlm.nih.gov/pubmed/24567510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311070 |
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