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Modular thermal sensors in temperature-gated transient receptor potential (TRP) channels

The molecular basis of the thermal sensitivity of temperature-sensitive channels appears to arise from a specific protein domain rather than integration of global thermal effects. Using systematic chimeric analysis, we show that the N-terminal region that connects ankyrin repeats to the first transm...

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Autori principali: Yao, Jing, Liu, Beiying, Qin, Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3131340/
https://ncbi.nlm.nih.gov/pubmed/21690353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105196108
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