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A thermodynamic framework for understanding temperature sensing by transient receptor potential (TRP) channels

The exceptionally high temperature sensitivity of certain transient receptor potential (TRP) family ion channels is the molecular basis of hot and cold sensation in sensory neurons. The laws of thermodynamics dictate that opening of these specialized TRP channels must involve an unusually large conf...

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Detalhes bibliográficos
Main Authors: Clapham, David E., Miller, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3241781/
https://ncbi.nlm.nih.gov/pubmed/22109551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117485108
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