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Kinetic and Energetic Analysis of Thermally Activated TRPV1 Channels

Thermal TRP channels are important for thermal sensation and nociception, but their gating mechanisms have remained elusive. With optically generated submillisecond temperature steps from 22°C to >60°C, we have directly measured the activation and deactivation kinetics of TRPV1 channels, and from...

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Hlavní autoři: Yao, Jing, Liu, Beiying, Qin, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941006/
https://ncbi.nlm.nih.gov/pubmed/20858418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.07.022
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