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DNA Basepair Step Deformability Inferred from Molecular Dynamics Simulations

The sequence-dependent DNA deformability at the basepair step level was investigated using large-scale atomic resolution molecular dynamics simulation of two 18-bp DNA oligomers: d(GCCTATAAACGCCTATAA) and d(CTAGGTGGATGACTCATT). From an analysis of the structural fluctuations, the harmonic potential...

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Main Authors: Lankaš, Filip, Šponer, Jiří, Langowski, Jörg, Cheatham, Thomas E.
格式: Artigo
語言:Inglês
出版: Biophysical Society 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303568/
https://ncbi.nlm.nih.gov/pubmed/14581192
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