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On the Use of Molecular Dynamics Simulations for Probing Allostery through DNA

A recent study described an allosteric effect in which the binding of a protein to DNA is influenced by another protein bound nearby. The effect shows a periodicity of ∼10 basepairs and decays with increasing protein-protein distance. As a mechanistic explanation, the authors reported a similar peri...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Dršata, Tomáš, Zgarbová, Marie, Jurečka, Petr, Šponer, Jiří, Lankaš, Filip
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4776040/
https://ncbi.nlm.nih.gov/pubmed/26827073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.12.039
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