Molecular Dynamics Simulations of Guanine Quadruplex Loops: Advances and Force Field Limitations

A computational analysis of d(GGGGTTTTGGGG)(2) guanine quadruplexes containing either lateral or diagonal four-thymidine loops was carried out using molecular dynamics (MD) simulations in explicit solvent, locally enhanced sampling (LES) simulations, systematic conformational search, and free energy...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Fadrná, Eva, Špačková, Nad'a, Štefl, Richard, Koča, Jaroslav, Cheatham, Thomas E., Šponer, Jiří
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2004
Ämnen:
Biophysical Theory and Modeling
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304345/
https://ncbi.nlm.nih.gov/pubmed/15240460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.034751
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk