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Isolation of high-affinity GTP aptamers from partially structured RNA libraries
Aptamers, RNA sequences that bind to target ligands, are typically isolated by in vitro selection from RNA libraries containing completely random sequences. To see whether higher-affinity aptamers can be isolated from partially structured RNA libraries, we selected for aptamers that bind GTP, starti...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129318/ https://ncbi.nlm.nih.gov/pubmed/12185247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.182095699 |
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