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In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers
Nucleic acid aptamers hold great promise for therapeutic applications due to their favorable intrinsic properties, as well as high-throughput experimental selection techniques. Despite the utility of the systematic evolution of ligands by the exponential enrichment (SELEX) method for aptamer determi...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7165443/ https://ncbi.nlm.nih.gov/pubmed/32234785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913242117 |
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