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In silico design and validation of high-affinity RNA aptamers targeting epithelial cellular adhesion molecule dimers
Nucleic acid aptamers hold great promise for therapeutic applications due to their favorable intrinsic properties, as well as high-throughput experimental selection techniques. Despite the utility of the systematic evolution of ligands by the exponential enrichment (SELEX) method for aptamer determi...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7165443/ https://ncbi.nlm.nih.gov/pubmed/32234785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1913242117 |
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