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Solution structure of an informationally complex high-affinity RNA aptamer to GTP

Higher-affinity RNA aptamers to GTP are more informationally complex than lower-affinity aptamers. Analog binding studies have shown that the additional information needed to improve affinity does not specify more interactions with the ligand. In light of those observations, we would like to underst...

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Bibliografiske detaljer
Main Authors: CAROTHERS, JAMES M., DAVIS, JONATHAN H., CHOU, JAMES J., SZOSTAK, JACK W.
Format: Artigo
Sprog:Inglês
Udgivet: Copyright 2006 by RNA Society 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1421093/
https://ncbi.nlm.nih.gov/pubmed/16510427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2251306
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