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Selection of cyclic peptide aptamers to HCV IRES RNA using mRNA display
The hepatitis C virus (HCV) is a positive strand RNA flavivirus that is a major causative agent of serious liver disease, making new treatment modalities an urgent priority. Because HCV translation initiation occurs by a mechanism that is fundamentally distinct from that of host mRNAs, it is an attr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556359/ https://ncbi.nlm.nih.gov/pubmed/18824687 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805837105 |
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