Discovery of Cyclic Peptide Ligands to the SARS-CoV-2 Spike Protein Using mRNA Display

[Image: see text] The COVID-19 pandemic, caused by SARS-CoV-2, has led to substantial morbidity, mortality, and disruption globally. Cellular entry of SARS-CoV-2 is mediated by the viral spike protein, and affinity ligands to this surface protein have the potential for applications as antivirals and...

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I publikationen:ACS Cent Sci
Huvudupphovsmän: Norman, Alexander, Franck, Charlotte, Christie, Mary, Hawkins, Paige M. E., Patel, Karishma, Ashhurst, Anneliese S., Aggarwal, Anupriya, Low, Jason K. K., Siddiquee, Rezwan, Ashley, Caroline L., Steain, Megan, Triccas, James A., Turville, Stuart, Mackay, Joel P., Passioura, Toby, Payne, Richard J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2021
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8189037/
https://ncbi.nlm.nih.gov/pubmed/34230894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c01708
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