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Neutrophils Interact with Adenovirus Vectors via Fc Receptors and Complement Receptor 1

Neutrophils are effectors of the innate immune response to adenovirus vectors. Following the systemic administration of Cy2-labeled AdLuc in mice, flow cytometry and PCR analysis of liver leukocytes revealed that 25% of recruited neutrophils interacted with adenovirus vectors. In vitro, flow cytomet...

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Detalhes bibliográficos
Main Authors: Cotter, Matthew J., Zaiss, Anne K., Muruve, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1287577/
https://ncbi.nlm.nih.gov/pubmed/16282462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.23.14622-14631.2005
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