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Neutralized Adenovirus-Immune Complexes Can Mediate Effective Gene Transfer via an Fc Receptor-Dependent Infection Pathway

Neutralization of adenovirus (Ad) by anti-Ad neutralizing antibodies in serum involves formation of Ad-immune complexes that prevent the virus from interacting with target cells. We hypothesized that Ad-immune complexes likely contain viable Ad vectors which, although no longer capable of gaining ac...

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Detalhes bibliográficos
Main Authors: Leopold, Philip L., Wendland, Rebecca L., Vincent, Theresa, Crystal, Ronald G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617312/
https://ncbi.nlm.nih.gov/pubmed/17005701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00512-06
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