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Differential Activation of Innate Immune Responses by Adenovirus and Adeno-Associated Virus Vectors
Adenovirus vectors induce acute inflammation of infected tissues due to activation of the innate immune system and expression of numerous chemokines and cytokines in transduced target cells. In contrast, adeno-associated virus (AAV) vectors are not associated with significant inflammation experiment...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology (ASM)
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155101/ https://ncbi.nlm.nih.gov/pubmed/11932423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4580-4590.2002 |
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