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Differential Activation of Innate Immune Responses by Adenovirus and Adeno-Associated Virus Vectors
Adenovirus vectors induce acute inflammation of infected tissues due to activation of the innate immune system and expression of numerous chemokines and cytokines in transduced target cells. In contrast, adeno-associated virus (AAV) vectors are not associated with significant inflammation experiment...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
2002
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC155101/ https://ncbi.nlm.nih.gov/pubmed/11932423 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4580-4590.2002 |
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