Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi

The increased resistance of the protozoan parasite Trypanosoma cruzi to nitro derivatives is one of the major problems for the successful treatment of Chagas' disease. In the present study, we have tested the effects of 1-O-hexadecylphosphocholine (miltefosine) against strains of T. cruzi that...

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Hlavní autoři: Saraiva, Victor B., Gibaldi, Daniel, Previato, José O., Mendonça-Previato, Lucia, Bozza, Marcelo T., Freire-de-Lima, Célio G., Heise, Norton
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC128733/
https://ncbi.nlm.nih.gov/pubmed/12384352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3472-3477.2002
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