Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi

The increased resistance of the protozoan parasite Trypanosoma cruzi to nitro derivatives is one of the major problems for the successful treatment of Chagas' disease. In the present study, we have tested the effects of 1-O-hexadecylphosphocholine (miltefosine) against strains of T. cruzi that are p...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Saraiva, Victor B., Gibaldi, Daniel, Previato, José O., Mendonça-Previato, Lucia, Bozza, Marcelo T., Freire-de-Lima, Célio G., Heise, Norton
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Experimental Therapeutics
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3472-3477.2002
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