Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi

The increased resistance of the protozoan parasite Trypanosoma cruzi to nitro derivatives is one of the major problems for the successful treatment of Chagas' disease. In the present study, we have tested the effects of 1-O-hexadecylphosphocholine (miltefosine) against strains of T. cruzi that are p...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Saraiva, Victor B., Gibaldi, Daniel, Previato, José O., Mendonça-Previato, Lucia, Bozza, Marcelo T., Freire-de-Lima, Célio G., Heise, Norton
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Experimental Therapeutics
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3472-3477.2002
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