Proinflammatory and Cytotoxic Effects of Hexadecylphosphocholine (Miltefosine) against Drug-Resistant Strains of Trypanosoma cruzi

The increased resistance of the protozoan parasite Trypanosoma cruzi to nitro derivatives is one of the major problems for the successful treatment of Chagas' disease. In the present study, we have tested the effects of 1-O-hexadecylphosphocholine (miltefosine) against strains of T. cruzi that...

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Autors principals: Saraiva, Victor B., Gibaldi, Daniel, Previato, José O., Mendonça-Previato, Lucia, Bozza, Marcelo T., Freire-de-Lima, Célio G., Heise, Norton
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
Matèries:
Experimental Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC128733/
https://ncbi.nlm.nih.gov/pubmed/12384352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3472-3477.2002
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