Structure-Function Relationships for Human Antibodies to Pneumococcal Capsular Polysaccharide from Transgenic Mice with Human Immunoglobulin Loci

To investigate the influence of antibody structure and specificity on antibody efficacy against Streptococcus pneumoniae, human monospecific antibodies (MAbs) to serotype 3 pneumococcal capsular polysaccharide (PPS-3) were generated from transgenic mice reconstituted with human immunoglobulin loci (...

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Dades bibliogràfiques

Publicat a:	Infect Immun
Autors principals:	Chang, Q., Zhong, Z., Lees, A., Pekna, M., Pirofski, L.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2002
Matèries:	Microbial Immunity and Vaccines
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4977-4986.2002
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