Structure-Function Relationships for Human Antibodies to Pneumococcal Capsular Polysaccharide from Transgenic Mice with Human Immunoglobulin Loci

To investigate the influence of antibody structure and specificity on antibody efficacy against Streptococcus pneumoniae, human monospecific antibodies (MAbs) to serotype 3 pneumococcal capsular polysaccharide (PPS-3) were generated from transgenic mice reconstituted with human immunoglobulin loci (...

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Podrobná bibliografie

Vydáno v:	Infect Immun
Hlavní autoři:	Chang, Q., Zhong, Z., Lees, A., Pekna, M., Pirofski, L.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2002
Témata:	Microbial Immunity and Vaccines
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4977-4986.2002
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