Structure-Function Relationships for Human Antibodies to Pneumococcal Capsular Polysaccharide from Transgenic Mice with Human Immunoglobulin Loci

To investigate the influence of antibody structure and specificity on antibody efficacy against Streptococcus pneumoniae, human monospecific antibodies (MAbs) to serotype 3 pneumococcal capsular polysaccharide (PPS-3) were generated from transgenic mice reconstituted with human immunoglobulin loci (...

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Bibliografske podrobnosti

izdano v:	Infect Immun
Principais autores:	Chang, Q., Zhong, Z., Lees, A., Pekna, M., Pirofski, L.
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2002
Teme:	Microbial Immunity and Vaccines
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12183544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.9.4977-4986.2002
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