High Potency of Indolyl Aryl Sulfone Nonnucleoside Inhibitors towards Drug-Resistant Human Immunodeficiency Virus Type 1 Reverse Transcriptase Mutants Is Due to Selective Targeting of Different Mechanistic Forms of the Enzyme

Samankaltaisia teoksia

• Drug Resistance Mutations in the Nucleotide Binding Pocket of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Differentially Affect the Phosphorolysis-Dependent Primer Unblocking Activity in the Presence of Stavudine and Zidovudine and Its Inhibition by Efavirenz
  Tekijä: Crespan, Emmanuele, et al.
  Julkaistu: (2005)
• Vif is an auxiliary factor of the HIV-1 reverse transcriptase and facilitates abasic site bypass
  Tekijä: Cancio, Reynel, et al.
  Julkaistu: (2004)
• Effects of Drug Resistance Mutations L100I and V106A on the Binding of Pyrrolobenzoxazepinone Nonnucleoside Inhibitors to the Human Immunodeficiency Virus Type 1 Reverse Transcriptase Catalytic Complex
  Tekijä: Locatelli, Giada A., et al.
  Julkaistu: (2004)
• Gln145Met/Leu Changes in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nucleoside and Nonnucleoside Analogs and Impair Virus Replication
  Tekijä: Paolucci, Stefania, et al.
  Julkaistu: (2004)
• Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs
  Tekijä: Maga, Giovanni, et al.
  Julkaistu: (2001)