Gln145Met/Leu Changes in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nucleoside and Nonnucleoside Analogs and Impair Virus Replication

The frequencies of multidrug resistance-associated mutations at codons 145, 151, and 69 of the human immunodeficiency virus (HIV) reverse transcriptase (RT) gene in strains from a group of 3,595 highly active antiretroviral therapy (HAART)-experienced patients were 0.22, 2.36, and 0.86%, respectivel...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Paolucci, Stefania, Baldanti, Fausto, Maga, Giovanni, Cancio, Reynel, Zazzi, Maurizio, Zavattoni, Maurizio, Chiesa, Antonella, Spadari, Silvio, Gerna, Giuseppe
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15561833/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.12.4611-4617.2004
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