Human Immunodeficiency Virus Type 1 Isolates with the Reverse Transcriptase (RT) Mutation Q145M Retain Nucleoside and Nonnucleoside RT Inhibitor Susceptibility

Q145M, a mutation in a conserved human immunodeficiency virus type 1 reverse transcriptase (RT) region, was reported to decrease susceptibility to multiple RT inhibitors. We report that Q145M and other Q145 mutations do not emerge with RT inhibitors nor decrease RT inhibitor susceptibility. Q145M sh...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Varghese, Vici, Mitsuya, Yumi, Shahriar, Rajin, Bachmann, Michael H., Fessel, W. Jeffrey, Kagan, Ron M., Shafer, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681550/
https://ncbi.nlm.nih.gov/pubmed/19223644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01593-08
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados