Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs

Combinations of reverse transcriptase (RT) inhibitors are currently used in anti-human immunodeficiency virus therapy in order to prevent or delay the emergence of resistant virus and to improve the efficacy against viral enzymes carrying resistance mutations. Drug-drug interactions can result in ei...

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Detalhes bibliográficos
Main Authors: Maga, Giovanni, Hübscher, Ulrich, Pregnolato, Massimo, Ubiali, Daniela, Gosselin, Gilles, Spadari, Silvio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90443/
https://ncbi.nlm.nih.gov/pubmed/11257034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.4.1192-1200.2001
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