Potentiation of Inhibition of Wild-Type and Mutant Human Immunodeficiency Virus Type 1 Reverse Transcriptases by Combinations of Nonnucleoside Inhibitors and d- and l-(β)-Dideoxynucleoside Triphosphate Analogs

Combinations of reverse transcriptase (RT) inhibitors are currently used in anti-human immunodeficiency virus therapy in order to prevent or delay the emergence of resistant virus and to improve the efficacy against viral enzymes carrying resistance mutations. Drug-drug interactions can result in ei...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Maga, Giovanni, Hübscher, Ulrich, Pregnolato, Massimo, Ubiali, Daniela, Gosselin, Gilles, Spadari, Silvio
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Antiviral Agents
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11257034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.4.1192-1200.2001
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