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Internal IgH class switch region deletions are position-independent and enhanced by AID expression
Ig heavy chain class switch recombination (CSR) involves a recombination/deletion mechanism that exchanges the expressed C(H) gene with a downstream C(H) gene. CSR is mediated by highly repetitive switch (S) region sequences and requires the activation-induced deaminase (AID). The S region 5′ of the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126611/ https://ncbi.nlm.nih.gov/pubmed/12114543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152333499 |
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