Internal IgH class switch region deletions are position-independent and enhanced by AID expression
Ig heavy chain class switch recombination (CSR) involves a recombination/deletion mechanism that exchanges the expressed C(H) gene with a downstream C(H) gene. CSR is mediated by highly repetitive switch (S) region sequences and requires the activation-induced deaminase (AID). The S region 5′ of the...
I tiakina i:
| I whakaputaina i: | Proc Natl Acad Sci U S A |
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| Ngā kaituhi matua: | , , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
National Academy of Sciences
2002
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126611/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12114543/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152333499 |
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