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GATA1-Mediated Megakaryocyte Differentiation and Growth Control Can Be Uncoupled and Mapped to Different Domains in GATA1

The DNA-binding hemopoietic zinc finger transcription factor GATA1 promotes terminal megakaryocyte differentiation and restrains abnormal immature megakaryocyte expansion. How GATA1 coordinates these fundamental processes is unclear. Previous studies of synthetic and naturally occurring mutant GATA1...

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Bibliografiske detaljer
Main Authors: Kuhl, Christiane, Atzberger, Ann, Iborra, Francisco, Nieswandt, Bernhard, Porcher, Catherine, Vyas, Paresh
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265752/
https://ncbi.nlm.nih.gov/pubmed/16166640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8592-8606.2005
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