GATA1-Mediated Megakaryocyte Differentiation and Growth Control Can Be Uncoupled and Mapped to Different Domains in GATA1

The DNA-binding hemopoietic zinc finger transcription factor GATA1 promotes terminal megakaryocyte differentiation and restrains abnormal immature megakaryocyte expansion. How GATA1 coordinates these fundamental processes is unclear. Previous studies of synthetic and naturally occurring mutant GATA1...

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Main Authors: Kuhl, Christiane, Atzberger, Ann, Iborra, Francisco, Nieswandt, Bernhard, Porcher, Catherine, Vyas, Paresh
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265752/
https://ncbi.nlm.nih.gov/pubmed/16166640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8592-8606.2005
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