Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

The megakaryocyte/erythroid transient myeloproliferative disorder (TMD) in newborns with Down syndrome (DS) occurs when Nterminal truncating mutations of the hemopoietic transcription factor GATA1, that produce GATA1short protein (GATA1s), are acquired early in development. Prior work has shown that...

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Yayımlandı:Haematologica
Asıl Yazarlar: Juban, Gaëtan, Sakakini, Nathalie, Chagraoui, Hedia, Hernandez, David Cruz, Cheng, Qian, Soady, Kelly, Stoilova, Bilyana, Garnett, Catherine, Waithe, Dominic, Otto, Georg, Doondeea, Jessica, Usukhbayar, Batchimeg, Karkoulia, Elena, Alexiou, Maria, Strouboulis, John, Morrissey, Edward, Roberts, Irene, Porcher, Catherine, Vyas, Paresh
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Fondazione Ferrata Storti 2020
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018159/
https://ncbi.nlm.nih.gov/pubmed/32527952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.244541
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