Oncogenic Gata1 causes stage-specific megakaryocyte differentiation delay

The megakaryocyte/erythroid transient myeloproliferative disorder (TMD) in newborns with Down syndrome (DS) occurs when Nterminal truncating mutations of the hemopoietic transcription factor GATA1, that produce GATA1short protein (GATA1s), are acquired early in development. Prior work has shown that...

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Publicado no:Haematologica
Main Authors: Juban, Gaëtan, Sakakini, Nathalie, Chagraoui, Hedia, Hernandez, David Cruz, Cheng, Qian, Soady, Kelly, Stoilova, Bilyana, Garnett, Catherine, Waithe, Dominic, Otto, Georg, Doondeea, Jessica, Usukhbayar, Batchimeg, Karkoulia, Elena, Alexiou, Maria, Strouboulis, John, Morrissey, Edward, Roberts, Irene, Porcher, Catherine, Vyas, Paresh
Formato: Artigo
Idioma:Inglês
Publicado em: Fondazione Ferrata Storti 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8018159/
https://ncbi.nlm.nih.gov/pubmed/32527952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.244541
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