GATA1-Mediated Megakaryocyte Differentiation and Growth Control Can Be Uncoupled and Mapped to Different Domains in GATA1

The DNA-binding hemopoietic zinc finger transcription factor GATA1 promotes terminal megakaryocyte differentiation and restrains abnormal immature megakaryocyte expansion. How GATA1 coordinates these fundamental processes is unclear. Previous studies of synthetic and naturally occurring mutant GATA1...

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Detalhes bibliográficos
Main Authors: Kuhl, Christiane, Atzberger, Ann, Iborra, Francisco, Nieswandt, Bernhard, Porcher, Catherine, Vyas, Paresh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1265752/
https://ncbi.nlm.nih.gov/pubmed/16166640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.19.8592-8606.2005
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