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GATA-2 Reinforces Megakaryocyte Development in the Absence of GATA-1
GATA-2 is an essential transcription factor that regulates multiple aspects of hematopoiesis. Dysregulation of GATA-2 is a hallmark of acute megakaryoblastic leukemia in children with Down syndrome, a malignancy that is defined by the combination of trisomy 21 and a GATA1 mutation. Here, we show tha...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2738300/ https://ncbi.nlm.nih.gov/pubmed/19620289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00482-09 |
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