טוען...
Ordered assembly of the V(D)J synaptic complex ensures accurate recombination
Recombination of gene segments at the immunoglobulin and T-cell receptor loci requires that the RAG1 and RAG2 proteins bring together DNA signal sequences (RSSs) with 12- and 23-bp spacers into a synaptic complex and cleave the DNA. A RAG1/2 multimer that can cleave both signals is shown to assemble...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Oxford University Press
2002
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126141/ https://ncbi.nlm.nih.gov/pubmed/12145216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf394 |
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