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Footprint Analysis of Recombination Signal Sequences in the 12/23 Synaptic Complex of V(D)J Recombination

In V(D)J joining of antigen receptor genes, two recombination signal sequences (RSSs), 12-RSS and 23-RSS, are paired and complexed with the protein products of recombination-activating genes RAG1 and RAG2. Using magnetic beads, we purified the pre- and postcleavage complexes of V(D)J joining and ana...

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Detalhes bibliográficos
Main Authors: Nagawa, Fumikiyo, Kodama, Masami, Nishihara, Tadashi, Ishiguro, Kei-ichiro, Sakano, Hitoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC139802/
https://ncbi.nlm.nih.gov/pubmed/12242298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.20.7217-7225.2002
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