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Autoubiquitylation of the V(D)J recombinase protein RAG1
V(D)J recombination, the rearrangement of gene segments to assemble Ig and T cell receptor coding regions, is vital to B and T lymphocyte development. Here, we demonstrate that the V(D)J recombinase protein RAG1 undergoes ubiquitylation in cells. In vitro, the RING finger domain of RAG1 acts as a ub...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
National Academy of Sciences
2003
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC307587/ https://ncbi.nlm.nih.gov/pubmed/14671314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2637012100 |
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