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Autoubiquitylation of the V(D)J recombinase protein RAG1

V(D)J recombination, the rearrangement of gene segments to assemble Ig and T cell receptor coding regions, is vital to B and T lymphocyte development. Here, we demonstrate that the V(D)J recombinase protein RAG1 undergoes ubiquitylation in cells. In vitro, the RING finger domain of RAG1 acts as a ub...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jones, Jessica M., Gellert, Martin
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2003
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC307587/
https://ncbi.nlm.nih.gov/pubmed/14671314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2637012100
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