Autoubiquitylation of the V(D)J recombinase protein RAG1
V(D)J recombination, the rearrangement of gene segments to assemble Ig and T cell receptor coding regions, is vital to B and T lymphocyte development. Here, we demonstrate that the V(D)J recombinase protein RAG1 undergoes ubiquitylation in cells. In vitro, the RING finger domain of RAG1 acts as a ub...
Сохранить в:
| Опубликовано в:: | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307587/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14671314/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2637012100 |
| Метки: |
Нет меток, Требуется 1-ая метка записи!
|