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Role of RAG1 autoubiquitination in V(D)J recombination

The variable domains of Ig and T-cell receptor genes in vertebrates are assembled from gene fragments by the V(D)J recombination process. The RAG1–RAG2 recombinase (RAG1/2) initiates this recombination by cutting DNA at the borders of recombination signal sequences (RSS) and their neighboring gene s...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Singh, Samarendra K., Gellert, Martin
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507250/
https://ncbi.nlm.nih.gov/pubmed/26124138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1510464112
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