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Crystal Structure of the V(D)J Recombinase RAG1-RAG2
V(D)J recombination in the vertebrate immune system generates a highly diverse population of immunoglobulins and T cell receptors by combinatorial joining of segments of coding DNA. The RAG1-RAG2 protein complex (RAG1/2) initiates this site-specific recombination by cutting DNA at specific sites fla...
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| Published in: | Nature |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4342785/ https://ncbi.nlm.nih.gov/pubmed/25707801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14174 |
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