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Assembly Pathway and Characterization of the RAG1/2-DNA Paired and Signal-end Complexes

Mammalian immune receptor diversity is established via a unique restricted set of site-specific DNA rearrangements in lymphoid cells, known as V(D)J recombination. The lymphoid-specific RAG1-RAG2 protein complex (RAG1/2) initiates this process by binding to two types of recombination signal sequence...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Lapkouski, Mikalai, Chuenchor, Watchalee, Kim, Min-Sung, Gellert, Martin, Yang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505528/
https://ncbi.nlm.nih.gov/pubmed/25903130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641787
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