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Riches in RAGs: Revealing the V(D)J recombinase through high resolution structures
Development of the adaptive immune system is dependent on V(D)J recombination, which forms functional antigen receptor genes through rearrangement of component gene segments. The V(D)J recombinase, consisting of recombination-activating proteins RAG1 and RAG2, guides the initial DNA cleavage events...
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| Pubblicato in: | Trends Biochem Sci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5182142/ https://ncbi.nlm.nih.gov/pubmed/27825771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.10.003 |
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