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Conversion of raft associated prion protein to the protease-resistant state requires insertion of PrP-res (PrP(Sc)) into contiguous membranes

Prion protein (PrP) is usually attached to membranes by a glycosylphosphatidylinositol-anchor that associates with detergent-resistant membranes (DRMs), or rafts. To model the molecular processes that might occur during the initial infection of cells with exogenous transmissible spongiform encephalo...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Baron, Gerald S., Wehrly, Kathy, Dorward, David W., Chesebro, Bruce, Caughey, Byron
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125906/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11867531/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.5.1031
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